JCM, Free Full-Text
Por um escritor misterioso
Last updated 08 setembro 2024
![JCM, Free Full-Text](https://www.mdpi.com/jcm/jcm-11-06089/article_deploy/html/images/jcm-11-06089-g001.png)
Non-syndromic tooth agenesis (ns-TA) is one of the most common dental anomalies characterized by the congenital absence of at least one permanent tooth (excluding third molars). Regarding the essential role of genetic factors in ns-TA aetiology, the present study aimed to identify novel pathogenic variants underlying hypodontia and oligodontia. In a group of 65 ns-TA patients and 127 healthy individuals from the genetically homogenous Polish population, the coding sequences of 423 candidate genes were screened using targeted next-generation sequencing. Pathogenic and likely pathogenic variants were identified in 37 (56.92%) patients, including eight nucleotide alternations of genes not previously implicated in ns-TA (CHD7, CREBBP, EVC, LEF1, ROR2, TBX22 and TP63). However, since only single variants were detected, future research is required to confirm and fully understand their role in the aetiology of ns-TA. Additionally, our results support the importance of already known ns-TA candidate genes (AXIN2, EDA, EDAR, IRF6, LAMA3, LRP6, MSX1, PAX9 and WNT10A) and provide additional evidence that ns-TA might be an oligogenic condition involving the cumulative effect of rare variants in two or more distinct genes.
![JCM, Free Full-Text](https://www.radiomuseum.org/images/radio/marshall_jim_ltd/jcm_2000_tsl_100_1807783.jpg)
Triple Super Lead JCM-2000 TSL 100 Ampl/Mixer Marshall, Jim
Solved Please Help Need ASAP Assembly Language Upload the
![JCM, Free Full-Text](https://media.sweetwater.com/m/products/image/4a94547b4dN19V6Ie36ZNCfcYxtfvVXPRj4k191c.wm-lw.jpg?quality=82&width=750&ha=4a94547b4d116a40)
Marshall JCM800 2203X 100-watt Tube Head
![JCM, Free Full-Text](https://pub.mdpi-res.com/jcm/jcm-11-05079/article_deploy/html/images/jcm-11-05079-g001-550.jpg?1662434345)
Des Blood Vr Death Marine - Colaboratory
Diseases of the skin: their constitutional nature and cure : Burnett, J. Compton (James Compton), 1840-1901? : Free Download, Borrow, and Streaming : Internet Archive
![JCM, Free Full-Text](https://external-preview.redd.it/fonua-blake-to-join-the-sharks-in-2025-v0-Yg5OBoAQTBJ_lEMVy3jCm-NUuD2_mN2BbahRYhYsTM4.jpg?auto=webp&s=ac8e4c1429f6d30fb7c86f900048947a2764100a)
Fonua-Blake to join the Sharks in 2025 : r/nrl
![JCM, Free Full-Text](https://www.mdpi.com/jcm/jcm-12-07655/article_deploy/html/images/jcm-12-07655-g001.png)
JCM, Free Full-Text
![JCM, Free Full-Text](https://www.mdpi.com/jcm/jcm-13-00013/article_deploy/html/images/jcm-13-00013-g001.png)
JCM, Free Full-Text
![JCM, Free Full-Text](https://climario.vteximg.com.br/arquivos/ids/187922-420-420/bomba.jpg?v=638011040093400000)
Soluções completas de refrigeração e climatização
Recomendado para você
-
Rubinstein-Taybi Syndrome08 setembro 2024
-
Rubinstein-Taybi Syndrome: A Complete Overview — DermNet08 setembro 2024
-
Rubinstein Taybi Syndrome: Most Up-to-Date Encyclopedia, News & Reviews08 setembro 2024
-
Figure 1. [Facial appearance of a girl age 11 years with FHS (SRCAP pathogenic variant p.Arg2444Ter)]. - GeneReviews® - NCBI Bookshelf08 setembro 2024
-
Clinical and mutational spectrum in Korean patients with Rubinstein–Taybi syndrome: The spectrum of brain MRI abnormalities - ScienceDirect08 setembro 2024
-
Legius Syndrome - an overview08 setembro 2024
-
Somatic and germ‐line mosaicism in Rubinstein–Taybi syndrome - Chiang - 2009 - American Journal of Medical Genetics Part A - Wiley Online Library08 setembro 2024
-
Identification of de novo EP300 and PLAU variants in a patient with Rubinstein–Taybi syndrome-related arterial vasculopathy and skeletal anomaly08 setembro 2024
-
Frontiers Behavioral and neuropsychiatric challenges across the lifespan in individuals with Rubinstein-Taybi syndrome08 setembro 2024
-
PDF) Identification of de novo EP300 and PLAU variants in a patient with Rubinstein–Taybi syndrome-related arterial vasculopathy and skeletal anomaly08 setembro 2024
você pode gostar
-
Create gamepass and badge icons for your roblox game by08 setembro 2024
-
NFL mock draft 2023: Second-round projections08 setembro 2024
-
Trusted insider corroborates Bluepoint Games' Bloodborne PS5 remaster - Xfire08 setembro 2024
-
Chisel (item) - Official Feed The Beast Wiki08 setembro 2024
-
Men 2 Piece Suit Black Tuxedo Suit Perfect for Wedding One08 setembro 2024
-
Apostila CPA10 Edgar Abreu08 setembro 2024
-
Game Jolt - Share your creations08 setembro 2024
-
1234567890 Vector Images (32)08 setembro 2024
-
Bus Simulator 21 shows off new multiplayer mode in gameplay trailer08 setembro 2024
-
Play The Game08 setembro 2024